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Human Topoisomerase II Beta

Human topoisomerase II beta is prepared by overexpressing in baculovirus-infected insect cells (Spodoptera frugiperda) and purifying it by methods developed in-house. Our enzyme is of ultra-high quality, allowing for relaxation assays as well as decatenation assays to be performed. We are also able to supply cleavage-grade human topo II. Please contact us for further information.


We have a range of products that will help your drug discovery efforts, whether you are looking for novel anti-infectives, or new anti-cancer compounds, we have a range of target enzymes, available with and without their substrates, in easy to use kits. We also supply different topological isoforms of our DNA substrates.

Don't see your required enzyme? Contact us to see if we can make it for you or visit our Custom Proteins page! 

Not doing drug discovery? Our enzymes and DNA substrates are of extremely high purity and quality, perfect for reliable results!

All of our enzymes can be supplied in large or bulk quantities or at higher concentrations. Please contact us for a quote!

Likewise, if you require enzymes with particular specifications (e.g. low endotoxin, DNase or RNase free, low bioburden etc.), please contact us.


You can contact us on +44(0) 1603 673590 or +44(0) 1603 673591, at [email protected] or by visiting our contact us page to discuss your requirements.

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