S. aureus Gyrase

Staphylococcus aureus DNA gyrase is a bacterial type II topoisomerase which can introduce negative supercoils into DNA. It is a target for both quinolone and coumarin drugs and can be used for screening potential antibacterial compounds. It is prepared by overexpressing the subunits in E. coli and then purified.

It is supplied as an A₂B₂ complex in Dilution Buffer. Store at -80 °C.

All enzyme is supplied with 5X concentrated Assay Buffer and Dilution Buffer which are also available separately. 1 U of gyrase will supercoil 0.5 µg relaxed pBR322 DNA in 30 minutes at 37 °C.

Please enquire for larger quantities/bulk orders.

See technical documents for more detailed information and lot specific activities.

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Cat no.	Product	Price	Quantity
SAG4001	S. aureus Gyrase (100 U) 100 U of S. aureus Gyrase supplied with 5X Assay Buffer and Dilution Buffer	£331.00
SAG4002	S. aureus Gyrase (500 U) 500 U of S. aureus Gyrase supplied with 5X Assay Buffer and Dilution Buffer	£1,168.00