Skip to main content

Bacterial Topoisomerases

As a leading provider of enzymes used in the discovery of new anti-infectives, we offer the widest range of bacterial DNA Gyrases and DNA Topoisomerase IV's, available as individual enzymes or in convenient assay kits with substrates. Explore our range, including enzymes with clinically-relevant mutations, individual subunits, and specific protein domains. Please contact us for Custom Mutations and Proteins. Beyond enzyme offerings, we go the extra mile by providing Screening Services and Mechanistic Studies.

We have a range of products that will help your drug discovery efforts, whether you are looking for novel anti-infectives, or new anti-cancer compounds, we have a range of target enzymes, available with and without their substrates, in easy to use kits. We also supply different topological isoforms of our DNA substrates.

Don't see your required enzyme? Contact us to see if we can make it for you or visit our Custom Proteins page! 

Not doing drug discovery? Our enzymes and DNA substrates are of extremely high purity and quality, perfect for reliable results!

All of our enzymes can be supplied in large or bulk quantities or at higher concentrations. Please contact us for a quote!

Likewise, if you require enzymes with particular specifications (e.g. low endotoxin, DNase or RNase free, low bioburden etc.), please contact us.


You can contact us on +44(0) 1603 673590 or +44(0) 1603 673591, at [email protected] or by visiting our contact us page to discuss your requirements.

Need help?
Call us on +44 (0) 1603 673591
Email on [email protected]

Search products