Inspiralis supplies high quality purified DNA substrates developed for use in topoisomerase assays. Positively supercoiled and negatively supercoiled and relaxed plasmid pBR322 DNA for topoisomerase relaxation and supercoiling assays, Kinetoplast DNA (catenated) kDNA for decatenation assays and linear DNA substrates for ATPase assays and markers.
We have a range of products that will help your drug discovery efforts, whether you are looking for novel anti-infectives, or new anti-cancer compounds, we have a range of target enzymes, available with and without their substrates, in easy to use kits. We also supply different topological isoforms of our DNA substrates.
Not doing drug discovery? Our enzymes and DNA substrates are of extremely high purity and quality, perfect for reliable results!
All of our enzymes can be supplied in large or bulk quantities or at higher concentrations. Please contact us for a quote!
Likewise, if you require enzymes with particular specifications (e.g. low endotoxin, DNase or RNase free, low bioburden etc.), please contact us.